Peptide Half-Life Calculator
See how much of a peptide remains after each half-life and roughly how long it takes to clear from the body — about five half-lives.
Half-Life Calculator
Enter a half-life and dose to model clearance over time
Clearance Curve
Enter a half-life and dose to see clearance
Amount remaining after each half-life
A half-life is the time it takes for half of a substance to be eliminated from the body. It's exponential — each half-life clears half of whatever remains, not half of the original dose.
Half-life drives dosing frequency. Peptides with short half-lives (minutes to hours) are typically dosed daily or multiple times per day, while those with long half-lives (days) are dosed weekly.
- 1Repeated dosing builds toward a steady state, where the amount entering the body equals the amount being cleared.
- 2Short half-life — dose more frequently to avoid big peaks and troughs in blood levels.
- 3Long half-life — once-weekly dosing keeps levels relatively flat; fewer injections needed.
Research Supplies
Planning a research protocol? Browse high-purity peptides and reconstitution supplies for laboratory use.
Shop Research PeptidesImportant Note
Half-life values vary by species, route, and formulation, and actual clearance is influenced by metabolism and kidney/liver function. This calculator is for research and educational purposes only. Nothing here is medical advice.